By Alex Matthews
San Diego, Nov. 23, 2008 -- Calit2's Center for Algorithmic and Systems Biology (CASB) recently hosted the UC San Diego Next-Generation Sequencing and Informatics Symposium. The Nov. 9-10 meeting provided an introduction to next-generation sequencing techniques, along with reports on the latest data analysis algorithms and tools. The first day focused on resequencing and de novo sequencing, and the algorithmic developmens that are driving the increase in data quality and volume in this field. On day two, the focus shifted to new applications, including digital gene expression, epigenetics, targeted sequencing, protein-DNA interactions, genotyping, SNP mapping, and more. Symposium presentations are now available for on-demand viewing; click on the image or video links below to watch individual talks. [Windows Media and broadband connection required].
SUNDAY | NOVEMBER 9 |
SESSION 1 | |
Welcome
Pavel Pevzner, Director, Center for Algorithmic and Systems Biolog; University of California, San Diego Length: 2:43 [video] |
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Human Re-sequencing for Variant Discovery in Cancer
Elaine Marids, Washington University Length: 48:00 [video] |
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Informatics and Experimental Strategies for De Novo Genome Sequencing with Short Reads
Elliott Margulies, National Human Genome Research Institute Length: 33:24 [video] |
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Identification of genetic variants within specific regions of the human genome
David Craig, Targeted Genetics Corporation (TGen) Length: 37:06 [video] |
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Targeted Human Genome Resequencing
Hanlee Ji, Stanford University Medical Center Length: 28:48 [video] |
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Assembling Short and error-Prone DNA Reads
Pavel Pevzner, University of California, San Diego Length: 39:41 [video] |
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Alta-Cyclic - A self Optimizing Base Caller for the Illumina Genome Analyzer
Yaniv Erlich, Cold Spring Harbor Labs Length: 28:17 [video] |
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De Novo Assembly of Short Reads as a Discovery Tool
Inanc Birol, BC Cancer Research Center Length: 54:41 [video] |
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De Novo Genome Sequencing of the Venturia inaequalis (apple scab) Using the Illumina Genome Analyser
Jasper Rees, University of the Western Cape, South Africa Length: 33:42 [video] |
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SLIPPER: An Iterative Mapping Pipeline for Short DNA Sequences
Terry Gaasterland, University of California, San Diego Length: 25:43 [video] |
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The Tuxedo tools: ultra high-throughput mapping of short sequencing reads
Cole Trapnell, University of Maryland Length: 32:36 [video] |
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SESSION 2
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WORKSHOPS
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Illumina
Length: 35:37 [video] |
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CLC Bio
Length: 23:31 [video] |
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DNA Star
Length: 42:56 [video] |
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Genome Quest
Length: 13:56 [video] |
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MONDAY
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NOVEMBER 10
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Mapping the Arabidopsis Epigenome and Transcriptome by Deep Sequencing
Ryan Lister, Salk Institute Length: 46:05 [video] |
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The long march: a sample preparation technique that enhances contig length and coverage by high-throughput short-read sequencing
Katherine Sorber, DeRisi Lab UCSF Length: 32:07 [video] |
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Rapid and Automated Building of a Human Genome from Aligned Short Reads
Richard Carter, Illumina, Inc. Length: 25:08 [video] |
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Analysis of the Human Transcriptome by Next-Gen Sequencing Gary Schroth, Illumina, Inc. Length: 50:45 [video] |
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Targeted resequencing with long range PCR and hybrid capture W. Richard McCombie, Cold Spring Harbor Laboratory Length: 35:51 [video] |
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From ChIP-chip to ChIP-Seq: unraveling the second code of the human genome Bing Ren, University of California, San Diego Video not available |
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Multiplex sequencing of organelle genomes using sequencing-by-synthesis technology: Insights from the first 100 plastomes Richard Cronn, Pacific Northwest Research Station - USDA Forest Service Length: 37:41 [video] |
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Unraveling gene regulation mechanisms: insights into chromatin modeling Karine Le Roch, University of California, Riverside Video not available |
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Genomic association study (CHIP-Seq) of Liver X receptors beta in combination with gene expression analysis Lana Garmire, Bioengineering, UC San Diego Length: 32:14 [video] |
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Empirical methods for controlling false positives and estimating confidence in ChIP-seq peaks David Nix, Huntsman Cancer Institute, Utah Length: 30:46 [video] |
Related Links
Next-Generation Sequencing and Informatics Symposium